Tumour Marker Requisition Pattern in a Tertiary Care Centre of Eastern Nepal

Background Tumor markers have been a valuable tool for decades to aid in the diagnosis, treatment, and monitoring of oncological diseases.
 Objective To retrospectively analyze requisition pattern tumor marker requests at largest tertiary care center eastern Nepal.
 Method A retrospective hospital-based cross-sectional study was conducted obtain data 5 common i.e., Alpha-Fetoprotein (AFP), Cancer antigen- 125 (CA-125), Carbohydrate antigen (CA) 19-9, Carcinoembryonic (CEA), Prostate-specific (PSA) analyzed Department Biochemistry B.P. Koirala Institute Health Sciences, Dharan, Nepal years.
 Result total 8716 tests over years. The most requested our hospital (48.77%) followed by antigen-125 (39.02%), (9.30%), (2.29%), 19-9 (0.63%) respectively. majority (Alpha-Fetoprotein, antigen-125, antigen) were from in-patient wards while majorly requisitioned out-patient department (OPD) [74%] respectively.
 Conclusion finding present suggest that though is one developing countries where specialized health services are limited only cities developed areas, burden disease high. Dharan small part serves population periphery. number requisitions as per laboratory significant (n=8716) period years few like Alpha-Fetoprotein, antigen, just initiated. Also, findings delineate outpatient departments more which might/ might not be inconsistent with preliminary diagnosis.